The new standard of care.

Clinical studies have long shown that buffered injections are less painful, faster acting, and for infected teeth, twice as likely to work1.

According to a recent article in Dr. Bicuspid, a leading dental industry publication:

Septodont's BufferPro and Onpharma’s Onset EZ "both offer convenient, simple-step buffering, and it’s fair to say both are major improvements to the clunky and expensive devices of the past."

"With all significant barriers to buffered anesthetics removed, a new standard of care has arrived.1"

What Key Opinion Leaders Say

"It is my strong belief that buffering of dental local anesthetics should be a routine part of all dental injections."

- Dr. Stanley Malamed

What is buffering?

Dental anesthetics contain acid to preserve their shelf life. The acid can be up to 25,000 times more acidic than human tissue.

"Buffering" refers to pH-balancing of the anesthetic prior to injection.

Decades of research have shown that removing the acid from local anesthetics produces faster onset, less injection pain, and increased reliability2, 3.

In 2026, Every injection should be buffered

Dental injections are acidic, too painful, slow-acting, and unreliable.

They don't have to be. Remove the acid.

With new innovations within the past year, buffering is now a convenient, simple-step process for dentists 1.

Ready to try (or recommend) buffering?

FOR DENTAL PROVIDERS

We are building our database of rapidly growing number of dentists who have transitioned to buffering. If you are currently buffering your anesthetic, let us know.

Petition for Acid-Free Anesthetics for All

Dear dental providers, organizaions, public health officials, and political representatives:

As an informed patient, I am aware that acid-free, buffered anesthetics are now the standard of care in dentistry and easy to integrate into dental workflows, and as the standard of care, should be used in 100% of dental injections.

I would NOT consent to a non-buffered injection for me or my family, and I believe other patients will feel the same once informed. Proper patient education should be prioritized, including requiring patient consent prior to administering a non-buffered injection.

I expect you will do the right thing. It's time to end the use of acidic, non-buffered anesthetics.